聚乳酸-庆大霉素珠粒对骨感染患者的临床疗效及其对症状改善的影响

Clinical Efficacy of Polylactate-gentamicin Pellets in Patients with Bone Infection and Its Influence on Symptom Improvement

目的:探究聚乳酸-庆大霉素珠粒对骨感染患者的临床疗效及其对症状改善的影响。方法:选取2016年5月—2019年5月间收治的骨感染患者60例资料,按治疗方法的不同将其分为对照组30例和观察组30例;对照组患者给予庆大霉素珠链治疗,观察组患者给予聚乳酸-庆大霉素珠粒局部治疗,比较两组患者治疗后的总有效率、复发率和临床症状复常时间的差异。结果:观察组患者治疗的总有效率高于对照组(P<0.05),术后复发率低于对照组(P<0.05),临床症状VAS评分值明显低于对照组(P<0.05)。结论:采用聚乳酸-庆大霉素珠粒局部治疗骨感染患者的疗效较为明显,有效提高了临床疗效,促进了切口的愈合,且复发率较低。

Objective: To investigate the clinical efficacy of polylactate-gentamicin pellets in patients with bone infection and its influence on symptom improvement. Methods: Data of 60 patients with bone infection admitted in hospital from May 2016 to May 2019 were selected and divided into 30 patients in the control group and 30 patients in the observation group according to different treatment methods. Patients in the control group were given gentamicin bead chain treatment, and patients in the observation group were given polylactate-gentamicin bead local treatment. The difference of the total effective rate, recurrence rate and clinical symptom recurrence time were compared between the two groups.Results: The total effective rate of treatment in the observation group was higher than that in the control group(P< 0.05), the postoperative recurrence rate was lower than that in the control group(P<0.05), and the VAS score of clinical symptoms was significantly lower than that in the control group(P<0.05). Conclusion: The local treatment of bone infection with polylactate-gentamicin pellet has obvious curative effect, effectively improves the clinical efficacy,promotes the wound healing, and the recurrence rate is lower.