1Spitz F, Furlong EE. Transcription factors: from enhancerbinding to developmental control. Nat Rev Genet 2012; 13:613-626.
2Blancafort P, Segal D J, Barbas CF 3rd. Designing transcription factor architectures for drug discovery. Mol Pharmacol 2004; 66:1361-1371.
3Sera T. Zinc-finger-based artificial transcription factors and their applications. Adv Drug Deliv Rev 2009; 61:513-526.
4Beerli RR, Segal D J, Dreier B, Barbas CF 3rd. Toward control- ling gene expression at will: specific regulation of the erbB- 2/HER-2 promoter by using polydactyl zinc finger proteins constructed from modular building blocks. Proc Natl Acad Sci USA 1998; 95:14628-14633.
5Beerli RR, Dreier B, Barbas CF 3rd. Positive and negative regulation of endogenous genes by designed transcription fac- tors. Proc NatI Acad Sci USA 2000; 97:1495-1500.
6Zhang F, Cong L, Lodato S, Kosuri S, Church GM, Arlotta P. Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription. Nat Biotechnol 2011; 29:149-153.
7Moscou M J, Bogdanove AJ. A simple cipher governs DNA recognition by TAL effectors. Science 2009; 326:1501.
8Boch J, Scholze H, Schornack S, et al. Breaking the code of DNA binding specificity of TAL-type IIl effectors. Science 2009; 326:1509-1512.
9Maeder ML, Linder S J, Reyon D, et al. Robust, synergistic regulation of human gene expression using TALE activators. Nat Methods 2013; 10:243-245.
10Perez-Pinera P, Ousterout DG, Brunger JM, et al. Synergistic and tunable human gene activation by combinations of syn- thetic transcription factors. Nat Methods 2013; 10:239-242.