摘要
聚集诱导发光(AIE)是指发光体由于聚集而发射荧光,具有AIE特性的发光体被称之为AIEgens。传统荧光材料在聚集或团聚状态时容易出现聚集诱导淬灭(ACQ),与之相反,AIE不受ACQ效应干扰,在生物医学应用方面展现着巨大潜力。该文将概述AIE的发光机制和性能特点,并对其纳米材料在肿瘤的生物成像和成像引导下治疗方面的最新研究进展进行综述。
Aggregation-induced emission(AIE)refers to an uncommon phenomenon that some fluorogens are weakly emissive in solution but become intensely florescent in aggregated state.Fluorogens with the characteristics of AIE are called AIEgens.Traditional dyes often suffer from a common photophysical phenomenon named aggregation-caused quenching(ACQ).As an anti-ACQ phenomenon,AIE shows great potential in biomedical applications.In this paper,the flurescence mechanism and characteristics of AIE are summarized,and the recent advances of aggregation-induced emission in tumor diagnosis and therapy is reviewed.
作者
何玉芳
唐文洁
江新青
He Yufang;Tang Wenjie;Jiang Xinqing(Department of Radiology,Guangzhou First People′s Hospital,the Second Affiliated Hospital of South China University of Technology,Guangzhou 510180,China)
出处
《中华核医学与分子影像杂志》
CAS
北大核心
2020年第6期373-377,共5页
Chinese Journal of Nuclear Medicine and Molecular Imaging
基金
国家自然科学基金(81571665)
广州市科技项目(2019-03-01-04-2024-0008)。
关键词
肿瘤
纳米粒
荧光
聚集诱导发光
发展趋势
Neoplasms
Nanoparticles
Fluorescence
Aggregation-induced emission
Trends
