临床药师参与防治术后感染多重耐药菌的作用

Analysis of the Role of Clinical Pharmacists in the Prevention and Treatment of Multiple Drug-Resistant Bacteria After Operation

目的探讨临床药师参与防治术后感染多重耐药菌的作用。方法选取于抚顺市中医院2015年2月至2016年1月接受手术治疗的患者300例为对照组,2018年2月至2019年1月接受手术治疗的患者300例为观察组。对照组未实施药学监护,观察组实施药学监护方案,比较两组的干预效果。结果观察组术后感染率及多重耐药菌感染率低于对照组(P<0.05);观察组干预后各项抗菌药物不合理用使用率低于对照组(P<0.05);观察组干预后感染及多重耐药相关知识了解程度显著高于对照组(P<0.05);观察组干预后急性生理与慢性健康评分表(APACHEⅡ)评分显著高于对照组(P<0.05)。结论临床药师在围手术期采用药学监护,有助于降低术后感染多重耐药菌风险,提高防治效果。

Objective To analyze the role of clinical pharmacists in the prevention and treatment of multiple drug-resistant bacteria after operation.Methods A total of 300 patients admitted in the Department of Pharmacy,Fushun Hospital of Chinese Medicine,from February 2015 to January 2016 were selected as the control group and 300 patients who were treated from February 2018 to January 2019 were as the observation group.The former did not carry out pharmaceutical care,and the latter carried out pharmaceutical care plan,and the intervention effects of the 2 groups was compared.Results The postoperative infection rate and the infection rate of multiple drug resistant bacteria in the observation group were lower than those in the control group and and differences are statistically significant(P<0.05),and the unreasonable drug use rate in the observation group was lower than that in the control group(P<0.05).The knowledge of infection and multiple drug resistance in the observation group was significantly higher than that in the control group.The APACHEⅡscore in the observation group was significantly higher than that in the control group and differences are statistically significant(P<0.05).Conclusion The use of pharmaceutical care by clinical pharmacists during perioperative period is helpful to reduce the risk of multiple drug-resistant bacteria after operation and improve the prevention and treatment effects.