摘要
体外膜肺氧合(ECMO)在很多危重症患者中可以提供心肺功能的支持,但是ECMO本身可引起全身炎性反应,导致急性肾衰竭及多脏器功能障碍等的风险增加,影响患者的预后。本文针对ECMO治疗中炎性反应的机制、危害及治疗措施的进展进行综述,以期为减轻ECMO相关炎性反应,改善患者临床预后,以及为后续研究提供思路。
Extracorporeal membrane oxygenation(ECMO)can provide support for cardiopulmonary function in many critically ill patients,but ECMO itself can cause systemic inflammatory reaction,lead to acute renal failure,multiple organ failure and other risks,and affect the prognosis of patients.This article reviews the mechanism,harm and treatment of inflammatory reaction in ECMO treatment,with a view to providing ideas for alleviating the inflammatory reaction associated with ECMO,improving clinical prognosis and follow-up research.
作者
稂与恒
李彤
胡晓旻
赵成秀
郑伟锋
马群兴
宁萌
高征
Lang Yu-heng;Li Tong;Hu Xiao-min;Zhao Cheng-xiu;Zheng Wei-feng;MaQun-xing;Ning Meng;Gao Zheng(Heart Center,Tianjin Thind Ceutral Hospinl,Tianjin Key Laboratory of Arifieial Cell,Arifeciad Cell Engineering Technology Reseurch Center of Public Heath Minisry,Tiarjin 300170,China)
出处
《中国急救医学》
CAS
CSCD
北大核心
2020年第5期461-465,共5页
Chinese Journal of Critical Care Medicine
基金
天津市自然科学基金(19JCYBJC26000)。
关键词
体外膜肺氧合(ECMO)
炎性反应
细胞因子
Extracorporeal membrane oxygenation(E CMO)
Inflammatory reaction
Cytokines