美沙拉嗪联合益生菌治疗溃疡性结肠炎35例疗效观察

Mesalazine plus Probiotics in the Treatment of Ulcerative Colitis:Effect Observation on 35 Cases

为观察美沙拉嗪联合益生菌治疗溃疡性结肠炎(UC)患者的疗效,将UC患者70例随机分为对照组和观察组,每组35例。对照组给予美沙拉嗪治疗,观察组给予美沙拉嗪联合益生菌治疗,观察2组患者的临床疗效炎症因子水平、疼痛程度及不良反应发生率。结果显示,治疗后观察组患者在临床疗效和炎症因子水平方面均优于对照组(P<0.05),观察组疼痛评分及不良反应发生率均低于对照组(P<0.05)。结果表明,美沙拉嗪联合益生菌治疗UC疗效显著,可明显减轻患者痛苦,且不良反应少,值得临床推广应用。

This study was to investigate the effect of mesalazine plus probiotics in the treatment of ulcerative colitis(UC),randomly divided 70 UC patients into control group(35 cases,only mesalazine)and observation group(35 cases,mesalazine plus probiotics);then,observed and compared both groups’clinical effect,inflammatory factory’s level,pain degree,and unward reaction.As results,in clinical effect and inflammatory factory’s level observation group was superior to control group(P<0.05);in pain score and untoward reaction incidence observation group was lower than control group(P<0.05).Results show that mesalazine plus probiotics has more better effect,can reduce patients’pain,and its untoward reaction also is less.It is worthy of popularization and application.