摘要
随着非小细胞肺癌(NSCLC)生存期的延长,脑转移成为其重要的失败模式。预防性脑照射(PCI)对于小细胞肺癌具有重要作用,但其在NSCLC中的价值尚存争议。本文就NSCLC PCI的作用、脑转移高危因素、PCI介入时间、PCI剂量分割、PCI不良反应等方面进行文献综述。
Brain metastasis has become a major failure pattern with the prolonged survival of patients with non-small cell lung cancer(NSCLC).Prophylactic cranial irradiation(PCI)has been proven to play a significant role in small cell lung cancer,whereas its value in NSCLC is still controversial.Therefore,this article reviewed the role of PCI in NSCLC,high-risk factors of brain metastasis,timing,dose fraction and toxicity of PCI,etc.
作者
张阳
李红伟
刘建辉
宋轶鹏
Zhang Yang;Li Hongwei;Liu Jianhui;Song Yipeng(Department of Radiation Oncology,Qingdao University Medical College Affiliated Yantai Yuhuangding Hospital,Yantai 264000,China)
出处
《中华放射肿瘤学杂志》
CSCD
北大核心
2020年第6期486-490,共5页
Chinese Journal of Radiation Oncology
基金
山东省自然科学基金(ZR2016HM17、ZR2016HB39、ZR2018BH028)。
关键词
肺肿瘤
预防性脑照射
研究进展
Lung neoplasm
Prophylactic cranial irradiation
Research progress
