自适应光学视网膜成像系统的激光安全分析

Laser Exposure Safety Analysis for Adaptive Optics Retinal Imaging System

在研究自适应光学(AO)视网膜成像系统的光辐射安全时,通常未考虑成像光与信标光的光谱带宽和双光束叠加效应。根据ICNIRP标准提出了一种光辐射安全分析方法。首先确定宽光谱光束照射视网膜时的辐亮度计算方法,然后分析双光束照射视网膜时的最大允许照射量(MPE),最后根据视网膜辐亮度和MPE制定了激光安全分析流程。将满足各种人眼视网膜成像系统照明条件的AO扫频光学相干层析成像系统作为实例,分析辐亮度和辐亮度极限,并与其他方法相比较来检验所提方法的正确性。所提方法适用于结合和未结合AO技术的各种人眼视网膜成像系统,可为人眼激光安全分析计算提供参考。

Generally speaking,the optical radiation safety analysis of an adaptive optics(AO)retinal imaging system does not currently consider the spectral bandwidth and superposition effect of imaging and beacon lights.To solve these problems,we propose a radiation safety analysis method that conforms to the international commission on non-ionizing radiation protection(ICNIRP)standard.First,the radiance calculation method is determined when a broadband spectral beam irradiates retina.Then,the maximum permissible exposure(MPE)is analyzed when retina is irradiated by two beams.The exposure safety analysis process is finally developed from the obtained retinal radiance and MPE.An AO swept-source optical coherence tomography imaging system,which covers the illumination conditions of various human retinal imaging systems,is considered as an example to calculate the radiance as well as the maximum radiance.The validity of the proposed method is verified by comparing with other methods.The proposed method is suitable for various human retinal imaging systems with and without AO technology,and it can provide a reference for calculating the safety level of human eye exposure to radiation.