微生态制剂联合伴同疗法根除幽门螺杆菌感染的分析及临床研究

Analysis and Clinical Study of Micro-ecological Preparation Combined with Concomitant Therapy for Eradication of Helicobacter Pylori Infection

目的:探讨微生态制剂联合伴同疗法根除幽门螺杆菌感染的效果。方法:选取笔者所在医院2017年6月-2019年6月收治的40例幽门螺杆菌阳性患者,将患者随机分为两组,对照组行伴同疗法治疗,研究组行微生态制剂联合伴同疗法治疗,对比2周疗程后幽门螺杆菌根除率与不良反应发生率。结果:研究组幽门螺杆菌根除率为95.0%,高于对照组的65.0%,差异有统计学意义(P<0.05)。对照组不良反应发生率为15.0%,研究组不良反应发生率为5.0%,差异无统计学意义(P>0.05)。结论:微生态制剂联合伴同疗法治疗幽门螺杆菌感染的根除率较高,且不良反应发生率较低,更具有临床应用价值,值得推广应用。

Objective:To study the effect of microecological preparation on the eradication of Helicobacter pylori infection.Method:A total of 40 Helicobacter pylori positive patients admitted to our hospital from June 2017 to June 2019 were selected,the patients were randomly divided into two groups,the control group was treated with homotherapy,and the study group was treated with microecological agents combined with homotherapy,the eradication rate and the incidence of adverse reactions of Helicobacter pylori after two weeks of treatment were compared.Result:The Helicobacter pylori eradication rate in the study group was 95.0%,which was higher than 65.0%in the control group,the difference was statistically significant(P<0.05).The incidence of adverse reactions was 15.0%in the control group and 5.0%in the study group,there was no statistically significant difference(P>0.05).Conclusion:The eradication rate of microecological agents combined with concomitant therapy in the treatment of Helicobacter pylori infection is high,and the incidence of adverse reactions is low,which is more valuable for clinical application and is worth popularizing.