老年人脂肪肌的研究进展

Research progress on fatty muscle in elderly people

骨骼肌脂肪浸润是影响骨骼肌质量的重要因素,也是骨骼肌衰老的重要病理特征.骨骼肌脂肪浸润是一种病理诊断,衰老相关的骨骼肌脂肪浸润能否被视为一种老年综合征有待研究.鉴于骨骼肌脂肪浸润与脂肪肝都属于体内脂肪异位沉积,两者均与糖尿病和高脂血症密切相关,在病理基础和危险因素方面具有的高度相似性,我们建议临床使用脂肪肌(fatty muscle)这一名词表述衰老相关的骨骼肌脂肪浸润.现对老年人脂肪肌近年来的研究进展进行全面综述.

Myosteatosis is an important factor affecting skeletal muscle quality and a hallmark of skeletal muscle aging.Myosteatosis is a pathological condition.Whether aging-related myosteatosis can be considered as a geriatric syndrome remains unclear.Given that both myosteatosis and fatty liver are ectopic fat deposition,are associated with diabetes and hyperlipidemia,and share a similar pathological basis and risk factors,we recommend using the term"fatty muscle"to describe aging-related myosteatosis in clinical practice.This article comprehensively reviews recent research progress on"fatty muscle"in the elderly.