肠道菌群在内脏痛中枢机制中的作用

The role of intestinal flora in the central mechanism of visceral pain

肠道菌群是人体内具有重要调节作用的"器官",近年来肠道菌群在内脏痛中的作用逐渐被认识并广泛研究,肠道菌群在内脏痛的进一步发展、治疗和干预措施中已经展现较明显的潜力。虽然已进行了较多的基础研究,但对肠道菌群参与内脏疼痛的潜在机制仍然处于探索阶段。文章主要从4个方面阐述了肠道菌群与内脏痛中枢机制之间的相互作用,为进一步研究肠道菌群在内脏痛中的作用提供理论基础,并为治疗内脏痛提供新的靶点。

Intestinal flora is an important and regulating organ in the human body.In recent years,the role of intestinal flora in visceral pain has been gradually recognized and widely studied.Intestinal flora has shown obvious potential in further development,treatment,and intervention of visceral pain.Although more basic research has been done,the potential mechanism of intestinal flora involved in visceral pain is still in the exploring stage.This review focuses on the interaction between intestinal flora and visceral pain central mechanism through four aspects,which provides a theoretical basis for further study of the mechanism and provides new targets for the treatment of visceral pain.