基于中医传承辅助平台探讨治疗健忘的核心方

Based on TCM inheritance auxiliary platform to discuss views on amnesia

目的:对中国中医科学院广安门医院老年科杨戈主任医师临床治疗健忘的处方规律进行数据挖掘,以期为临床用药提供思路和方法。方法:规范整理后,人工录入401诊次病历,运用"中医传承辅助平台(V2.5)"的频数分析、关联规则、复杂系统熵聚类及无监督的熵层次聚类等算法对单药、对药、角药及配伍规律等进行研究。结果:治疗健忘最常见单药为黄芪(336次,83.79%);最常见的配伍规律为龟甲,远志->石菖蒲(0.9931);龟甲,龙骨,远志->石菖蒲(0.9927)。结论:老年人肾精亏虚,气虚不足以推动血液运行而致血瘀,堵塞脑窍可发为健忘,经过探究发现杨戈主任医师临床常以补肾填精、益气通络、开窍醒神药物治疗老年患者健忘,可以优先选择黄芪、川芎、红花、远志、石菖蒲、龙骨、龟甲、地龙、白术、葛根、甘草、大枣等药物。

Objective This paper was aimed to study prescription regularity on amnesia treatment of Yang Ge professor.Methods A total of 401 prescriptions were obtained by manual retrieval.TCM Inheritance Auxiliary Platform(V 2.5)was used in the study of single drug,pair of drugs,triangle drug,and compatibility laws by using association rules,complex systems entropy clustering and unsupervised entropy hierarchical clustering.Rseults The most common herbal medicine is Huangqi(336 times,83.79%);the common compatibility laws were Guijia,Yuanzhi->Shichangpu(0.9931);Guijia,Longgu,Yuanzhi->Shichangpu(0.9927).Conclusion Amnesia on old mainly caused by qi deficiency and blood stasis.It is often treated with herb of orifice-opening,tonify qi and free the collateral vessels,such as Huangqi,Chuanxiong,Honghua,Yuanzhi,Shichangpu,Longgu,Guijia,Dilong,Baizhu,Gegen,Gancao,Dazao and so on.