稳心颗粒联合美托洛尔治疗CHD伴心律失常疗效及对24h动态心电图的影响

Curative Effect of Wenxin Granule Combined with Metoprolol on Patients with CHD and Arrhythmia and its Effects on 24h Dynamic Electrocardiogram

目的观察稳心颗粒联合美托洛尔治疗CHD伴心律失常患者疗效及对24h动态心电图的影响。方法将我院42例CHD伴心律失常患者随机分为观察组和对照组。对照组在常规治疗基础上加用美托洛尔治疗;观察组在常规治疗基础上加用美托洛尔、稳心颗粒治疗。治疗四周后观察两组患者的治疗效果、出现的不良反应及心电图变化。结果观察组的治疗总有效率高于对照组(P<0.05);观察组PR间期、QTc间期高于对照组,QRS波时限低于对照组(P<0.05);不良反应发生率(P>0.05)。结论稳心颗粒联合美托洛尔治疗冠心病合并心律失常效果较好。

Objective To observe the curative effect of Wenxin granule combined with metoprolol on patients with CHD and arrhythmia and its effects on 24h dynamic electrocardiogram(DCG).Methods Forty-two patients with CHD and arrhythmia in the hospital were randomly divided into observation group and control group.On basis of routine treatment,control group was treated with metoprolol,while observation group was treated with metoprolol and Wenxin granules.After 4 weeks of treatment,curative effect,adverse reactions and DCGchanges in both groups were observed.Results The total response rate of treatment in observation group was higher than that in control group(P<0.05).PR interval and QTc interval in observation group were higher than those in control group,while time limit of QRS wave was lower than that in control group(P<0.05).There was no significant difference in incidence of adverse reactions between the two groups(P>0.05).Conclusion The curative effect of Wenxin granule combined with metoprolol is good on CHD combined with arrhythmia.