维拉帕米注射治疗皮肤瘢痕疙瘩的效果观察

Effect of Verapamil Injection in the Treatment of Skin Keloids

目的观察维拉帕米注射治疗皮肤瘢痕疙瘩的效果。方法选取本院2018年10月~2019年9月收治的皮肤瘢痕疙瘩患者90例,按随机编号法分为对照组和观察组,各45例。对照组给予曲安奈德注射治疗,观察组给予维拉帕米注射治疗。比较两组患者治疗前后瘢痕疙瘩长、宽、厚,治疗有效率,温哥华瘢痕评定量表(VSS)评分以及不良反应的情况。结果治疗后,观察组瘢痕疙瘩长、宽、厚,治疗有效率,VSS评分和不良反应率均明显优于对照组(P<0.05)。结论维拉帕米注射治疗皮肤瘢痕疙瘩具有疗效好、不良反应率低的优点,值得临床推荐。

Objective To observe the effect of verapamil injection in the treatment of skin keloids.Methods Ninety patients with skin keloids treated in the hospital between October 2018 and September 2019 were selected and divided into the control group and the observation group by the random numbering method,with 45 cases in each group.The control group were treated with triamcinolone acetonide injection and the observation group were treated with verapamil injection.The length,width and thickness of keloids before and after treatment,effective rates of treatment,the Vancouver Scar Scale(VSS)scores and adverse reactions were compared between the two groups.Results After treatment,the length,width and thickness of keloids,effective rate of treatment,VSS score and the incidence of adverse reactions in the observation group were significantly better than those in the control group(P<0.05).Conclusion Verapamil injection for treating skin keloids has advantages of good curative effect and low incidence of adverse reactions.