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尼可地尔联合氯吡格雷对冠心病心绞痛的临床疗效 被引量:2

Effect of nicodil combined with clopidogrel on angina pectoris and coronary heart disease with endothelial and cardiac function
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摘要 目的:探究尼可地尔联合氯吡格雷用药对冠心病心绞痛患者的临床疗效。方法:选取我院2018年4月至2019年5月心内科收治的冠心病心绞痛患者70例。按照随机数字表随机分为对照组和观察组,各35例。对照组患者给予尼可地尔治疗,观察组在对照组基础上联合氯吡格雷治疗,治疗15天后,观察两组患者的临床治疗总有效率、血管内皮功能(NO、ET-1和RHI)和心脏功能(LVEF、LVESD、LVEDD、CO及CI)。结果:观察组患者的总有效率优于对照组(P<0.05);观察组治疗后ET-1水平低于对照组(P<0.05),NO及血管内皮指数高于对照组(P<0.01);观察组治疗后,与对照组比LVEF、LVESD、LVEDD、CO及CI水平改善(P<0.05)。结论:尼可地尔联用氯吡格雷治疗冠心病心绞痛疗效显著,同时可显著改善心脏指数和血管内皮指数。
作者 何咏聪 叶泽兵 He Yongcong;Ye Zebing
出处 《甘肃医药》 2020年第1期43-45,共3页 Gansu Medical Journal
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