fMRI技术在基于临床针刺镇痛机制研究领域的文献计量学分析及评述

The Bibliometric Analysis and Review of fMRI in the Research Field of Clinical Acupuncture Analgesia Mechanism

目的系统分析基于功能磁共振(Functional Magnetic Resonance Imaging,fMRI)技术在针刺镇痛机制临床研究领域文献的基本信息、研究内容和结果,了解该领域研究热点及发展现状,为其临床应用提供理论依据。方法检索中英文7个数据库中fMRI应用于针刺镇痛机制临床研究的相关文献,使用文献计量学方法对文献进行归纳和总结。结果共纳入105篇文献,研究生理状态49篇,病理状态56篇,涉及疾病15种,以偏头痛(18篇)为研究热点。fMRI在脑功能研究领域中以功能分化和功能整合为原则进行数据分析。结论通过纳入文献研究结果发现,针刺可以调节默认网络、中央执行网络"、疼痛矩阵"、额顶网络、感觉运动网络等多个脑区,通过大脑皮层和皮层下脑区相互作用以达到镇痛作用。

The basic information,research content and results of the literature on the clinical research of acupuncture analgesia mechanism based on functional magnetic resonance imaging(fMRI)technology were systematically analyzed to understand the research hotspots and development status of this field and provide theoretical basis for its clinical application.Literature related to clinical studies on the mechanism of acupuncture analgesia using fMRI in 7 databases in Chinese and English was searched,and literatures were summarized and summarized by bibliometrics method.A total of 105 articles were included,including 49 articles on physiological state and 56 articles on pathological state,involving 15 diseases.A total of 18 articles(32.4%)focused on migraine.In the field of brain function research,fMRI conducts data analysis based on the principle of functional differentiation and functional integration.According to the results of the literature included,acupuncture can regulate default network,central executive network,“pain matrix”,frontal and parietal network,sensorimotor network and other brain regions,and achieve analgesic effect through the interaction between cerebral cortex and subcortical brain regions.