基于有限元方法的不同类型肿瘤微波消融区域分布

Temperature Distribution of Microwave Ablation Regions of Different Types of Tumor Tissues Based on Finite Element Method

为了研究微波消融技术在不同类型肿瘤中治疗效果,基于有限元分析方法,建立耦合电磁场和生物传热过程的微波消融模型,研究了单缝同轴微波消融天线在脑白质肿瘤、脑灰质肿瘤、乳腺脂肪肿瘤、乳腺腺体肿瘤、肾脏肿瘤、肺部肿瘤(充气和未充气状态下)、肝脏肿瘤和肌肉瘤中比吸收率、消融区域温度分布及消融灶形态。结果表明:由于各种类型组织热物性的不同,导致微波消融天线在不同类型的肿瘤组织中消融灶的形态和有效损毁区域的覆盖范围存在显著差异,其中微波消融天线在由脂肪组织包围的乳腺癌肿瘤中形成的消融灶呈水滴状,消融区域完全覆盖肿瘤,但沿着消融天线的穿刺方向存在尾迹;天线在未充气状态下的肺部组织中形成的消融区域对健康组织的损伤要大于充气状态下,同时消融天线在其他实质型组织中形成的消融区域基本呈现椭圆形,消融区域整体小于肺部和乳腺的消融灶,可见微波消融天线在乳腺和充气状态下肺部组织的肿瘤消融治疗中可以获得更加有效的治疗效果。

In order to study the effect of microwave ablation technique in different types of tumors,a microwave ablation model of coupled electromagnetic field and bioheat transfer process was established based on finite element simulation analysis method.The temperature distribution of white matter tumor,gray matter tumor,breast tumor,breast gland tumor,kidney tumor,lung tumor(inflated and uninflated state),liver tumor and muscle tumor in microwave ablation process were studied.The results show that due to the different physical properties of various types of tissue,the morphology of the microwave ablation antenna in different types of tumor tissue and the coverage of the effective damage area are significantly different.The ablation lesion formed in the breast cancer tumor surrounded by adipose tissue is in the shape of a drop,and the ablation area completely covers the tumor,but there is a trail along the direction of the ablation antenna;The ablation zone formed in the lung tissue in the uninflated state is greater than in the inflated state,The ablation zone formed in other parenchymal types of tissue is basically elliptical,the ablation zone as a whole is smaller than the lesions in the lungs and mammary glands.It can be seen that microwave ablation technology can obtain more effective therapeutic effects in ablation of breast and lung tumors.