影响双相情感障碍患者自杀行为的危险因素调查

Investigation analysis on risk factors of suicide behavior of bipolar disorder patients

目的探讨影响双相情感障碍(BPD)患者自杀行为的危险因素,并提出预防措施。方法对540例BPD患者进行随访调查,根据患者是否发生自杀行为将其分为自杀行为组(194例)和无自杀行为组(346例);采用单因素比较法和多因素逐步logistic回归法筛选影响BPD患者自杀行为的危险因素。结果 540例BPD患者自杀行为率为35.93%;影响BPD患者自杀行为的危险因素包含女性(OR=1.846)、家族自杀史(OR=3.117)、重大精神创伤史(OR=4.154)、抑郁程度(OR=5.254)、人际关系差(OR=2.801)、无价值感或负罪感(OR=3.615)等。结论 BPD患者具有较高的自杀行为率,且影响其自杀行为的独立危险因素较多;应引起精神科医生的重视,早期采取预防措施,减少自杀倾向和自杀行为。

Objective To explore the risk factors of suicide behavior of bipolar disorder(BPD)patients,and provide prevention measures for it.Methods Totally 540 BPD patients were carried out a follow-up survey,and these patients were divided into the suicide behavior group(194 cases)and the non-suicide behavior group(346 cases)according to suicide behavior.The risk factors of suicide behavior of BPD patients were respectively screened by single factor and multiple factors stepwise Logistic regression methods.Results The rate of suicide behavior in these 540 cases of BPD was 35.93%.The risk factors of suicide behavior of BPD patients included female(OR=1.846),family suicide history(OR=3.117),history of major trauma(OR=4.154),depression degree(OR=5.254),poor interpersonal relationships(OR=2.801)and a sense of worthlessness or guilt(OR=3.615).Conclusion BPD patients have a high rate of suicide behavior,and there are many independent risk factors affecting suicide behavior.Psychiatrists should pay attention,and prevention measures should be adopted early,to reduce suicidal tendencies and suicide behavior.