2011-2018年四川省茂县出生缺陷监测结果分析

Surveillance results of birth defects in Mao County,2011-2018

目的分析四川省茂县出生缺陷监测及诊断情况,进一步制定出生缺陷三级防控措施。方法统计分析茂县2011-2018年出生缺陷监测资料。结果茂县2011-2018年监测围生儿8141例,出生缺陷60例,出生缺陷发生率为73.70/万。前五位出生缺陷顺位是多指/趾(18.43/万)、唇裂(7.37/万)、唇裂合并腭裂(7.37/万)、马蹄内翻足(6.14/万)及小耳(6.14/万)。围生儿出生缺陷相关因素中男性高于女性,居住在乡村、母亲年龄小于20岁的出生缺陷发生率较高。出生缺陷的诊断主要依据临床、产后确诊(90.2%)。转归构成:88.5%活产,9.8%死胎,1.6%活产。结论降低出生缺陷发生率需进一步加强三级预防措施,完善妇幼保健服务体系。

Objective To investigate the incidnece and diagnosis of birth defects in Maoxian County,Sichuan Province,and to provide scientific basis for strengthening the three-level prevention and control of birth defects.Methods According to the requirement of Maternal and Child Health Surveillance Scheme in China provided by the China Birth Defect Monitoring Program,we collected the data of birth defects in Mao County from 2011 to 2018,and then statistically analyzed these data.Results a total of 8141 perinatal infants were monitored,and among them 60 birth defects were detected from 2011 to 2018 in Maoxian County.The incidence of birth defects was 73.70/10000.The top five birth defects were polydactyly(1843/10000),cleft lip(37/10000),cleft lip with cleft palate(37/10000),horseshoe varus foot(64/10000),and small ear(61.14/10000).The incidence rate of birth defects was higher in the males than in the females.The incidence of birth defects is higher in rural areas and mothers younger than 20 years old.The diagnosis of birth defects was mainly based on clinical and postpartum diagnosis(90.2%).The outcome was 88.5%of live births,9.8%of stillbirths and 1.6%of live births.Conclusion it is necessary to further strengthen tertiary prevention so as to reduce the incidence of birth defects,and to improve maternal and child health care service system.