选择性剖宫产围手术期预防性应用抗菌药物的回顾性调查分析

Retrospective analysis on perioperative prophylactic use of antibiotics in selective cesarean

目的评价选择性剖宫产围手术期预防性抗菌药物应用的合理性。方法选取178例选择性剖宫产患者的病历资料,针对围术期预防性抗菌药物使用率以及用药时机、疗程、费用等情况统计分析。结果剖宫产围手术期预防性抗菌药物使用率100%;使用两种及以上抗菌药物的患者占50%;所有患者用药疗程均超过48 h;选用了《指导原则》范围以外的抗菌药物的患者占21.9%。结论剖宫产围术期预防用药部分品种选择不当、用量大,用药时间长,应按抗菌药物临床应用指导原则予以干预。

Objective To evaluate the rationality of the application of perioperative prophylactic use of antibiot⁃ics in selective cesarean.Methods 178 patients with selective cesarean section were selected.The perioperative prophy⁃lactic use rate of antibiotics,drug use time,course of treatment and cost were analyzed.Results The use rate of periop⁃erative prophylactic use of antibiotics in selective cesarean was 100%;50%of patients used more than two antibacterial drugs;all patients took medication for more than 48 hours;21.9%of patients used antibacterial drugs outside the scope of the"Guiding Principles".Conclusion Some varieties of perioperative prophylactic use of antibiotics are not proper⁃ly selected,the dosage is too large and the medication is used for a long time.Intervention should be conducted in accor⁃dance with the guidelines for clinical application of antibacterial drugs.