不同麻醉方法对老年颅内肿瘤患者术后不同时段认知功能临床疗效观察

Clinical effect of different anesthesia methods on cognitive function of elderly patients with intracranial tumor at different time after operation

目的:分析不同麻醉方法对老年颅内肿瘤患者术后不同时段认知功能的影响。方法:2018年9月-2019年8月收治老年颅内肿瘤患者60例,随机分为两组,各30例。试验组采用丙泊酚复合瑞芬太尼靶控静脉麻醉;对照组采用异氟醚吸入复合静脉麻醉。比较两组认知功能评分。结果:两组术后认知功能均有恢复,试验组术后认知功能评分恢复较快,术后2 d恢复至术前水平,但对照组术后2 d仍低于术前水平,差异有统计学意义(P<0.05)。结论:丙泊酚复合瑞芬太尼靶控静脉麻醉在现阶段临床效果较为优良,对老年颅内肿瘤患者术后认知功能影响相对较小。

Objective:To explore the influence of different anesthesia methods on cognitive function of elderly patients with intracranial tumor at different time after operation.Methods:From September 2018 to August 2019,60 elderly patients with intracranial tumors were selected and randomly divided into two groups of 30 cases in each.Propofol combined with remifentanil target controlled intravenous anesthesia was used in the experimental group and isoflurane inhalation combined intravenous anesthesia was used in the control group.We compared the cognitive function scores of the two groups.Results:The postoperative cognitive function was restored in both groups,in the experimental group,the score of cognitive function recovered rapidly,and it returned to preoperative level at 2 days after operation,however,the control group was still lower than the preoperative level at 2 days after operation,the difference was statistically significant(P<0.05).Conclusion:The clinical effect of target controlled intravenous anesthesia with propofol and remifentanil is better at this stage,it has little effect on the cognitive function after operation of the elderly patients with intracranial tumor.