应用有限元法定量分析绝经后女性骨强度的研究

Quantitative Analysis of Postmenopausal Female Bone Strength Using Finite Element Method

目的应用有限元法计算机辅助生物力学分析法评定绝经期女性骨强度值,判断其骨质疏松程度。方法收集已具有骨密度检查结果的23名绝经后女性股骨颈CT数据,对数据进行分割处理,同时创建有限元数学模型,把相应数据代入ANSYS分析软件进行结构力学分析,获取股骨上段的应力云图,分析研究对象的骨强度与骨密度情况。结果23例女性骨密度值为0.470~0.792 g/cm^2,骨强度值为1094~3078 N,均低于文献报道的正常成人左股骨上段骨强度值(约4000 N);ANSYS分析软件显示,骨强度与骨密度呈正相关(r=0.617,P<0.05)。结论绝经期女性骨强度与骨密度均低于正常人,应用有限元法计算出的骨强度定量值与骨密度值呈正相关,有限元法可用于定量评估骨强度。

Objective To use the finite element method computer-aided biomechanical analysis method to evaluate the bone strength value of menopausal women and determine the degree of osteoporosis.Methods Collecting the CT data of 23 postmenopausal female femoral necks with bone density examination results,segment the data,and create a finite element mathematical model,and substitute the corresponding data into ANSYS analysis software for structural mechanical analysis to obtain the stress cloud of the upper femur to analyze the bone strength and bone density of the research object.Results The bone mineral density of 23 women was 0.470~0.792 g/cm^2,and the bone strength value was 1094~3078 N,which were all lower than the bone strength value of normal adult left femur reported in the literature(about 4000 N);ANSYS analysis software showed that the bone strength,there was a positive correlation with bone density(r=0.617,P<0.05).Conclusion The bone strength and bone density of menopausal women are lower than those of normal people.The quantitative value of bone strength calculated by the finite element method is positively correlated with the bone density value.The finite element method can be used to quantitatively evaluate bone strength.