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胰岛素联合α-葡萄糖苷酶抑制剂治疗老年2型糖尿病的临床疗效 被引量:6

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摘要 目的:分析胰岛素联合α-葡萄糖苷酶抑制剂治疗老年2型糖尿病(T2DM)的临床疗效。方法:选取我院2018年1月—2019年5月老年T2DM患者80例,依据不同治疗方式分为联合组与单一组,各40例。单一组予以胰岛素(甘精胰岛素)治疗,联合组予以甘精胰岛素、α-葡萄糖苷酶抑制剂(阿卡波糖)联合治疗。比较两组治疗效果和治疗前、治疗后血糖水平[餐后2 h血糖(2 hPG)、糖化血红蛋白(HbA1c)、空腹血糖(FPG)]和胰岛功能指标(空腹C肽、餐后2 h C肽)。结果:两组总有效率对比,联合组97.50%(39/40)高于单一组的75.00%(30/40)(P<0.05);治疗后,联合组FPG、HbA1c、2 hPG水平低于单一组(P<0.05);治疗后,联合组空腹C肽、餐后2 h C肽高于单一组(P<0.05)。结论:甘精胰岛素、阿卡波糖联合治疗老年T2DM效果显著,可明显控制血糖水平,改善胰岛功能。
作者 孙静
出处 《北方药学》 2020年第5期100-101,共2页 Journal of North Pharmacy
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