期刊文献+

Luminal B-HER-2阴性乳腺癌和三阴型乳腺癌X线征象比较 被引量:5

Comparison Analysis of X-ray Signs Signs between Luminal B-HER-2(-)Breast Cancer and Triple negative Subtype Breast Cancer
原文传递
导出
摘要 目的探讨Luminal B-HER-2阴性型乳腺癌和三阴型(TN)乳腺癌临床病理特征及X线征象的差异。方法搜集行全数字化乳腺X线摄影并手术病理证实乳腺癌476例,对X线征象进行统计分析。结果肿块形态:Luminal B-HER-2阴性型不规则较多,TN型椭圆形较多。肿块密度:Luminal B-HER-2阴性型密度增高较多。肿块边缘:Luminal B-HER-2阴性型毛刺较多,TN型模糊较多。肿块长径:Luminal B-HER-2阴性型2~5 cm较多,TN型大于5 cm较多。钙化形态:Luminal B-HER-2阴性型细小多形性较多,TN型模糊不定形较多。其他征象:Luminal B-HER-2阴性型在淋巴结转移较多,皮肤乳头改变较多。象限:Luminal B-HER-2阴性在外上象限较多。结论Luminal B-HER-2阴性型乳腺癌和TN型乳腺癌在影像征象上有差异。 Objective To explore the differences in clinicopathological characteristics and X-ray signs of Luminal B-HER-2(-)breast cancer and triple negative breast cancer.Methods A total of 476 cases of breast cancer were confirmed by digital mammography and confirmed by surgical pathology.The X-ray signs were statistically analyzed.Results Mass morphology:Luminal B-HER-2(-)type had more irregularities,and triple-negative type had more oval shapes.Mass density:Luminal B-HER-2(-)type had increased density.Lump margin:Luminal B-HER-2(-)type has more burrs and triple-negative type has more blur.Tumor length:Luminal B-HER-2(-)type is more in 2-5 cm,and triple-negative type is more than 5 cm.Calcification morphology:Luminal B-HER-2(-)type has more small polymorphism,and more triple negative ambiguous indefinite shape.Other signs:Luminal B-HER-2(-)type has more metastasis in lymph nodes and more changes in skin and nipple.Quadrant:Luminal B-HER-2(-)has more upper quadrants.Conclusion Luminal B-HER-2(-)breast cancer and triple negative breast cancer have different imaging signs.
作者 张曦 汪湍 李莉 蔡斌 郭小明 武秀兰 ZHANG Xi;WANG Tuan;LI Li(Tumor Subsidiary Hospital of Xinjiang Medical University,Xinjiang,Urumqi 830011,P.R.China)
出处 《临床放射学杂志》 CSCD 北大核心 2020年第2期299-302,共4页 Journal of Clinical Radiology
基金 自治区卫生计生委青年医学科技人才专项科研项目基金资助项目(编号:XJWY-201809)。
关键词 乳腺癌 X线征象 病理组织学 Breast cancer X-ray signs Histopathology
  • 相关文献

参考文献7

二级参考文献60

  • 1<乳腺癌HER2检测指南>编写组,霍临明.乳腺癌HER2检测指南[J].中华病理学杂志,2006,35(10):631-633. 被引量:164
  • 2于慧,胡夕春.侵袭性细胞基底样乳腺癌的生物学特征[J].中华肿瘤防治杂志,2007,14(3):234-236. 被引量:4
  • 3陈莉颖,陈红风,付娜,叶媚娜.218例不同分子亚型浸润性乳腺癌患者的临床特征[J].现代肿瘤医学,2007,15(8):1094-1097. 被引量:12
  • 4Nielsen TO, Hsu FD, Jensen K, et aI. Immunohistochemical and clinical characterization of the Basal-like subtype of invasive breast cancer. Clin Cancer Res, 2004,10(16):5367-5374.
  • 5Yu K, Lee CH, Tap PH, et al. Conservation of breast cancer molecular subtypes and transcriptional patterns of tumor progression acrogs distinct ethnic populations. Clin Cancer Res, 2004,10 (16) :5508-5517.
  • 6Van De Rijn M, Perou CM, Tibshirani R, et al. Expression of cytokeratins 17 and 5 identifies a group of breast carcinomaswith poor clinical outcome. Am J Pathol, 2002,161(6) : 1991-1996.
  • 7Obenauer S, Hermann KP, Grabbe E. Applications and literature review of the BI-RADS classification. Eur Radiol, 2005, 15(5) : 1027-1036.
  • 8Perou CM, Serlie T, Eisen MB, et al. Molecular portraits of human breast tumors. Nature, 2000,406(17):747-753.
  • 9Calza S, Hall P, Auer G, et al. Intrinsic molecular signature of breast cancer in a population-based cohort of 412 patients. Breast Cancer Res, 2006,8(4) :R34.
  • 10Carey IrA, Perou CM, Livasy CA, et al. Race, breast cancer Lbtypes, and survival in the Carolina Breast Cancer Study. JAA, 2006,295(21) :2492 2502.

共引文献76

同被引文献29

引证文献5

二级引证文献7

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部