研究微创穿刺引流术治疗基底节区脑出血有效性及安全性

Study on the efficacy and safety of minimally invasive puncture and drainage in the treatment of cerebral hemorrhage in basal ganglia

目的:探讨采取微创穿刺引流术治疗基底节区脑出血患者的治疗效果。方法:2017年10月-2019年9月收治基底节区脑出血患者114例,分为两组,各57例。对照组采取药物保守治疗;观察组采取微创穿刺引流术治疗。比较两组治疗效果。结果:观察组治疗后卒中量表(NIHSS)评分明显低于对照组,日常生活活动能力量表(ADL)评分明显高于对照组,血清水通道蛋白4(AQP4)水平、Toll样受体4(TLR4)水平及脑水肿体积均明显低于对照组,观察组并发症率低于对照组,差异均有统计学意义(P<0.05)。结论:对基底节区脑出血患者采取微创穿刺引流术治疗可提高治疗效果,改善患者预后,且安全性良好。

Objective:To explore the effect of minimally invasive puncture and drainage in the treatment of cerebral hemorrhage in basal ganglia.Methods:From October 2017 to September 2019,114 patients with cerebral hemorrhage in basal ganglia were selected,they were divided into the two groups with 57 cases in each group.The control group was treated with conservative medicine.The observation group was treated with minimally invasive puncture and drainage.We compared the therapeutic effect of the two groups.Results:After treatment,the NIHSS score of the observation group was significantly lower than that of control group,ADL score was significantly higher than that of control group,AQP4 level,TLR4 level and brain edema volume were significantly lower than that of the control group,the complication rate of the observation group was lower than that of the control group,the differences were statistically significant(P<0.05).Conclusion:Minimally invasive puncture and drainage for patients with basal ganglia cerebral hemorrhage can improve the treatment effect and improve the prognosis of patients with good safety.