及早应用替罗非班对急性ST段抬高心肌梗死患者急诊介入治疗术后的影响

Effect of Early Application of Tirofiban on Patients with Acute ST-segment Elevation Myocardial Infarction after Emergency Interventional Therapy

目的探讨及早应用替罗非班对急性ST段抬高心肌梗死患者急诊PCI术后治疗效果的影响。方法抽取2018年5月-2019年5月在该院接受治疗的需要进行PCI手术患者118例,按照等差数列,首项为1,公差为7的方式将118例患者平均分为两组,即对照组与实验组,每组59例。对照组患者在冠状动脉造影时给予替罗非班,实验组在确诊后立即使用替罗非班,以3个月为观察周期,总结两组患者的恢复情况。结果实验组患者中3级患者的占91.52%,对照组3级患者占67.79%,差异有统计学意义(χ^2=3.256,P<0.05)。对照组与实验组患者不良事件发生率分别为11.86%、10.16%,差异有统计学意义(χ^2=6.426,P<0.05)。结论及早应用替罗非班对急性ST段抬高心肌梗死患者急诊介入治疗术后有显著作用,能够降低患者的手术风险,减少不良事件发生率,进一步提升治疗效果。

Objective To investigate the effect of early application of tirofiban on the efficacy of emergency PCI after acute ST segment elevation myocardial infarction.Methods From May 2018 to May 2019,118 patients who needed to undergo PCI operation in the hospital were selected.According to the series of equal difference,the first term was 1,and the tolerance was 7,the 118 patients were evenly divided into two groups.Namely,there were 59 patients in the control group and the experimental group.The patients in the control group were given tirofiban during coronary angiography,and the test group was given tirofiban immediately after diagnosis.The three-month observation period was used to summarize the recovery of the two groups of patients.Results Among the patients in the experimental group,Grade 3 patients accounted for 91.52%,and those in the control group Grade 3 patients accounted for 67.79%,the difference was statistically significant(χ^2=3.256,P<0.05).The incidences of adverse events in the control group and the experimental group were 11.86%and 10.16%,respectively,the difference was statistically significant(χ^2=6.426,P<0.05).Conclusion Early application of tirofiban has significant effects on patients with acute ST-segment elevation myocardial infarction after emergency interventional treatment,which can reduce the risk of surgery,reduce the incidence of adverse events,and further improve the treatment effect.