正常体重中年人体脂含量与腰椎和髋部骨密度相关性研究

Study on the correlation between body fat content and bone mineral density of lumbar spine and hip in Normal weight middle-aged people

目的探讨正常体重中年人体脂含量与腰椎和髋部骨密度(bone mineral density,BMD)相关性。方法选取499名成年受试者(平均年龄48.7岁),通过双能X线吸收测定法测量受试者BMD和体脂含量,采用多元线性回归分析和协方差分析评估BMD与体脂含量之间的关联。结果按体脂百分比截止值进行分组。体质量指数为18.5~22.9 kg/m2的男性临界值分别为20.6%和25.7%,而女性的临界值分别为33.4%和36%。体脂百分比往往与BMD呈负相关。身体脂肪百分比的增加与正常体重中年人的BMD降低有关。正常体重人群体脂百分比对BMD的影响在男性中比女性更明显。结论体重正常的中年男性和女性体脂百分比与骨密度呈负相关,这种关联在男性中比在女性中更为突出。

Objective To explore the the correlation between body fat content and bone mineral density of lumbar spine and hip in Normal weight middle-aged people.Methods This study included 499 adults(mean age,48.7 years).BMD and body fat were measured using dual-energy X-ray absorptiometry.Multiple linear regression analyses and analysis of covariance were used to assess the association between BMD and body fat.Body fat percentage was grouped by cut-off values.Results Grouped according to the cut-off value of body fat percentage.The cut-off values were 20.6%and 25.7%for men with a body mass index of 18.5-22.9 kg/m2,while the cut-off values were 33.4%and 36%for women.Body fat percentage tended to be negatively associated with BMD.Increased body fat percentage was associated with reduced BMD in normal-weight middle-aged adults.The effects of body fat percentage on BMD in normal-weight individuals were more pronounced in men than in women.Conclusion There was a negative correlation between BMD and body fat percentage in middle-aged men and women with normal body weight.This association was more prominent in men than in women.