早期非小细胞肺癌的微创介入治疗

Minimally Invasive Therapies for Early Stage Non-small Cell Lung Cancer

肺癌是目前全球最常见的癌症和癌症死亡的主要原因,其中非小细胞肺癌(non-small-cell lung cancer,NSCLC)约占肺癌总数的85%。随着计算机断层扫描(computed tomography,CT)等影像学筛查手段得到不断普及,肺癌的病理类型从以往以晚期中央型肺鳞癌为主,转变为现在的以早期周围型磨玻璃样结节等为表现的肺腺癌为主。肺癌的早诊早治有着重要意义,而微创介入技术的不断发展完善,使得肺癌治疗有了更多的选择,例如立体定向放射、经皮穿刺消融、支气管介入等。本文将就目前临床常见的这些微创介入治疗的作用原理、优势、不足及展望做一评述。

Lung cancer is the most common cancer and the leading cause of cancer death in the world,among which non-small cell lung cancer(NSCLC)accounts for about 85%of the total lung cancer.With the widespread of computed tomography(CT)and other imaging screening methods,the pathological types of lung cancer have changed from central squa-mous cell carcinoma to the early-stage lung adenocarcinoma,which is manifested as isolated pulmonary nodules and ground glass nodules on CT.Early diagnosis and treatment of lung cancer is of crucial clinical significance,and the continuous develop-ment and improvement of minimally invasive interventional techniques provide more options for lung cancer treatment,such as stereotactic radiation,percutaneous ablation,and bronchial intervention.This paper will make a review on the principle,advantages,disadvantages and prospects of minimally invasive interventional therapy commonly used in clinical practice.