摘要
目的探讨新型冠状病毒肺炎(corona virus disease 2019,COVID-19)的临床特点,为其早期诊断和治疗提供依据。方法回顾性分析40例COVID-19确诊患者的临床资料,包括一般资料、临床表现及体征、影像学特征、实验室结果和治疗方法。结果 40例患者中25例(62.5%)与确诊病例有密切接触史,15例(37.5%)有武汉/湖北旅居史,13例(32.5%)为重症。首次入院症状中发热37例(体温≥37.5℃)(92.5%)和咳嗽26例(65.0%)是最常见的症状,典型的胸部CT影像学表现是磨玻璃影37例(92.5%),淋巴细胞计数减少有28例(70.0%),38例(95.0%)进行抗病毒治疗。结论 COVID-19具有一定的临床特征,典型影像学特征结合流行病学史和核酸检测阳性应考虑诊断为COVID-19。
Objective To explore the clinical characteristics of corona virus disease 2019(COVID-19)and to provide basis for early diagnosis and treatment.Methods The clinical data of 40 patients confirmed by COVID-19 were analyzed retrospectively,including general data,clinical manifestations and signs,imaging features,laboratory results and treatment methods.Results Among 40 patients,25(62.5%)had a history of close contact with the confirmed cases,15(37.5%)had a history of traveling or living in Wuhan/Hubei,and 13(32.5%)were severe.On admission,37 patients of fever(body temperature≥37.5℃)(92.5%)and 26 patients of cough(65.0%)were the most common symptoms.The typical chest CT manifestations were ground glass shadows in 37 cases(92.5%),lymphopenia in 28 cases(70.0%)and antiviral therapy in 38 cases(95.0%).Conclusions COVID-19 had certain clinical characteristics.Typical imaging features combined with epidemiological history and positive nucleic acid test should be considered as a diagnosis of COVID-19.
作者
马骏
吕佳妤
董领
陈添泉
郑碧霞
杜忠衡
MA Jun;LYU Jiayu;DONG Ling;CHEN Tianquan;ZHENG Bixia;DU Zhongheng(Department of Pathology,the First Affiliated Hospital of Wenzhou Medical University,Wenzhou 325000,China;Department of General Medicine,the Affiliated Kangning Hospital of Wenzhou Medical University,Wenzhou 325000,China;Department of Respiratory Medicine,the Third Affiliated Hospital of Wenzhou Medical University,Wenzhou 325200,China;Medical Affairs Office,the Affiliated Kangning Hospital of Wenzhou Medical University,Wenzhou 325000,China;Injection Transfusion Center,the First Affiliated Hospital of Wenzhou Medical University,Wenzhou 325000,China;Department of Accupuncture,the First Affiliated Hospital of Wenzhou Medical University,Wenzhou 325200,China)
出处
《健康研究》
CAS
2020年第3期273-276,共4页
Health Research
基金
国家自然科学基金项目(31900685)
温州市基础性医疗卫生科技项目(Y20190198)。