2型糖尿病视网膜病变的相关危险因素分析

Analysis of Risk Factors of Retinopathy in Type 2 Diabetes Mellitus

目的调查我院内分泌科住院的2型糖尿病(DM)患者的视网膜病变(DR)的相关危险因素,分析在院糖尿病患者预防视网膜病变发生的策略.方法随机抽取2018年1—12月在本溪市中心医院内分泌科住院的2型DM患者作为研究对象,根据有无视网膜病变分为DR组与非DR组,记录所有研究对象的一般情况、实验检查指标以及DR发生情况,比较两组研究对象之间上述资料的差异性,并筛选视网膜病变的危险因素.结果共纳入2型DM患者698例,其中患有视网膜病变者187例.Logistic回归分析显示DM病程、糖化血红蛋白水平、尿微量白蛋白是视网膜病变发生的独立危险因素(P<0.05).结论D R的发生是多种因素共同作用的结果,D M病程,糖化血红蛋白水平,尿微量白蛋白是DR发生的独立危险因素.

Objective To investigate the risk factors of diabetic retinopathy(DR)in patients with type 2 diabetes mellitus(DM)in the Department of endocrinology of our hospital,and to analyze the prevention strategy of diabetic retinopathy in type 2 DM inpatients Methods We randomly selected type 2 DM patients hospitalized in the Endocrinology Department of Benxi Central Hospital from January to December 2018 as the study object.According to whether there is retinopathy,they were divided into DR group and non DR group.The general condition,experimental examination indicators and DR occurrence of all cases were recorded and compared.The risk factors of retinopathy were evaluated.Results A total of 698 patients with type 2 DM were finally included,and 187 patients had rctinopathy.Logistic regression analysis showed that course of DM,glycosylated hemoglobin level and microalbuminuria were in dependent risk factors for retinopathy(P<0.05).Conclusion The occurrence of DR is the combination of multiple factors.The course of DM,the level of glycosylated hemoglobin and urine microalbumin are the independent risk factors of DR.