2013~2018年我院呼吸道感染患者9种病原体IgM抗体检测结果分析

Analysis of IgM antibody test results of 9 pathogens in patients with respiratory tract infections in our hospital from 2013 to 2018

目的分析呼吸道感染病原体分布特点,为治疗呼吸道感染提供病原体证据。方法选取惠州市第一人民医院2013~2018年临床诊断为呼吸道感染患者的血标本,采用间接免疫荧光法(IFA)检测9种病原体IgM抗体,分析9种病原体在年龄和季节的分布差异。结果13345例患者9种病原体IgM抗体总阳性率为42.17%,IgM抗体阳性率排名前三的病原体为肺炎支原体(31.17%)、乙型流感病毒(13.38%)、副流感病毒(7.78%)。少年组肺炎支原体和乙型流感病毒IgM抗体阳性率均高于老年组。流感病毒IgM抗体阳性率以春冬两季较高,嗜肺军团菌IgM抗体阳性率以秋冬较高,而肺炎支原体IgM抗体阳性率无明显季节差异。结论呼吸道感染的病原体具有年龄和季节分布特点,但肺炎支原体和乙型流感病毒仍是各年龄及各季节中最主要的病原体。

Objective To analyze the distribution of respiratory tract infection pathogens and provide evidence for the treatment of respiratory tract infection.Methods The blood samples of patients with respiratory tract infection in the First Peopole′s Hospital of Huizhou from 2013 to 2018 were detected by indirect immunofluorescence(IFA),and the distribution difference of 9 respiratory pathogens in age and season was analyzed.Results The total positive rate of IgM antibody among 9 pathogens in 13345 patients was 42.17%,and the top three pathogens in IgM antibody positive rate were Mycoplasma pneumoniae(31.17%),Influenza B virus(13.38%)and Parainfluenza virus(7.78%).The positive rates of IgM antibody to Mycoplasma pneumoniae and Influenza B virus in the juvenile group were higher than those in the elderly group.The positive rate of IgM antibody of Influenza virus was higher in spring and winter,while that of Legionella pneumophila was higher in autumn and winter.However,there was no significant seasonal difference in the IgM antibody positive rate of Mycoplasma pneumoniae.Conclusion The pathogens of respiratory tract infection were related to age and season,but Mycoplasma pneumoniae and Influenza B virus were still the most important pathogens of all ages and seasons.