视网膜疾病药物研究进展

Advances in drug research for retinal diseases

视网膜疾病是常见的致盲性眼病之一,其发病机制复杂,对视功能损伤大。常见的视网膜疾病有年龄相关性黄斑变性、糖尿病性视网膜病变、视网膜静脉阻塞等。目前视网膜疾病治疗分为非药物治疗和药物治疗,药物包括抗氧化剂、抗炎剂、视循环调节剂、细胞治疗产品、抗血管内皮生长因子(VEGF)药物等,其中抗VEGF药物发展较好。

Retinal disease,which causes server visual impairment,is one of the common blinding eye diseases with complicated pathogenesis.Common retinal diseases include age-related macular degeneration,diabetic retinopathy,retinal vein occlusion,etc.Currently,the treatment of retinal diseases can be divided into non-drug treatment and drug treatment,including antioxidants,anti-inflammatory agents,visual circulation modulators,cell therapy products,anti-VEGF drugs and enterotrophin,among which anti-VEGF drugs are relatively well developed.