低聚肽对PVA/PEG复合薄膜相容性的影响

Effect of Oligopeptide on Compatibility of PVA/PEG Composite Film

以α-氨基酸为起始材料合成了低聚肽(TEA),通过溶液共混法将其引入聚乙二醇与PVA的复合体系中,使用不同分子量的PEG,制备了一系列PEG/TEA/PVA共混膜。试验了不同分子量PEG与TEA和PVA的相互作用,并分析了TEA对PEG/PVA复合体系相容性的影响。结果表明,TEA改变了PEG与PVA的相互作用模式,当PEG分子量较低时,PEG优先与TEA通过分子间作用力形成自组装微区,均匀分布于PVA连续相中,随着PEG的分子量增大,自组装微区的体积逐渐增大,PEG与TEA的相互作用随着距离的增加而减弱。当PEG分子量达到4 000时,PEG与PVA的链段缠结作用远大于TEA与PEG的相互作用,TEA分子分散在PEG/PVA体系中,在分子间的芳基堆砌作用驱动下,TEA自组装成纤丝。

Using a kind ofα-amino acid derivatived oligopeptide(TEA),the oligopeptide was introduced into the composite system of polyethylene glycol and PVA by solution blending.The interaction between different molecular weight PEG and TEA and PVA was tested,and the effect of TEA on the compatibility of PEG/PVA composite system was analyzed.The results showed that the introduction of TEA changed the interaction mode between PEG and PVA.The volume of self-assembly micro area increased with PEG molecular weight increased,which formed different morphology due to dynamic of intermolecular action.When the molecular weight of PEG reached 4000,the entanglement between PEG and PVA was much greater than that between TEA and PEG.TEA molecules were dispersed in PEG/PVA system.Driven by intermolecular aryl stacking,TEA self-assembled into filaments.