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卡双平联合诺和锐30治疗2型糖尿病临床观察

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摘要 2型糖尿病的发病机制主要是患者存在胰岛素抵抗和/或胰岛B细胞功能衰竭两个基本病理生理学缺陷。高血糖诱发和加重胰岛B细胞损伤和胰岛素抵抗。在2型糖尿病后期,胰岛B细胞功能损害更加明显,需要补充外源胰岛素控制血糖水平,胰岛素的使用使患者体重增加,再次加重胰岛素抵抗。使用胰岛素增敏剂可解决胰岛素抵抗,但仍会导致体重增加,而使用二甲双胍可以减轻体重。本研究探讨吡格列酮二甲双胍(卡双平)联合预混胰岛素治疗2型糖尿病的疗效及安全性。
出处 《中国现代医药杂志》 2020年第6期71-73,共3页 Modern Medicine Journal of China
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