心力衰竭与跌倒风险相关性的meta分析及系统评价

Meta analysis and systematic evaluation of the correlation between heart failure and the risk of falls

目的系统评价心力衰竭疾病与跌倒风险的关系。方法计算机检索PubMed,Web of Science,Cochrane Library,EMbase,以及中国生物医学文献数据库(CBM)、中国期刊全文数据库(CNKI)和万方数据库中有关心力衰竭与跌倒风险相关性的中英文横断面研究、队列研究和病例对照研究,检索日期均为建库至2019年1月。两名研究者单独提取资料并进行文献质量评价。结果共纳入6篇研究,154269例患者中心力衰竭4840例。meta分析结果显示,心力衰竭是跌倒的危险因素,OR=1.55,95%CI(1.20-1.99)。描述性分析结果显示,心力衰竭患者发生一次跌倒和反复跌倒的风险均高于研究中的其他亚组。结论患有心力衰竭疾病会增加跌倒的风险。

Objective To evaluate systematically the relationship between heart failure diseases and the risk of falls.Methods The computer search of PubMed,Web of Science,Cochrane Library,EMbase,and CBM,CNKI,and Wanfang databases on Chinese and English cross-sectional studies,cohort studies,and case-control studies on the correlation between heart failure and fall risk was performed,and the search dates were all from the establishment of the database to January 2019.The two researchers independently extracted data and conducted evaluation of literature quality.Results A total of 6 studies were included,and in 154,269 patients,there were 4,840 patients with heart failure.The results of the meta analysis showed that heart failure was the risk factor for falls,OR=1.55,95%CI(1.20-1.99).The results of the descriptive analysis showed that patients with heart failure had a higher risk of single and repeated falls than other subgroups in the study.Conclusion The heart failure disease increased the risk of falling.