同时性多原发肺癌29例诊治体会

Synchronous multiple primary lung cancer:a report on 29 cases

目的探讨同时性多原发肺癌(sMPLC)的诊断和治疗方法。方法随机抽取2012年1月至2015年12月于江南大学附属医院行手术切除的sMPLC患者29例,男17例,女12例。癌灶数目2个者23例,>2个者6例;癌灶位于同侧者15例,双侧者14例,并给予相应手术治疗。统计其生存时间及生存率。结果29例患者均于胸腔镜下顺利完成手术,其中行规范肺叶+亚肺叶切除术15例,行肺癌亚肺叶切除术14例,平均生存时间为33个月,3年生存率为58.6%,双侧多原发肺癌患者预后较单侧预后稍差。结论临床医师应提高对sMPLC的重视度,并早期诊断,采取以手术治疗为主的积极综合性治疗措施,可延长患者生存时间。

Objective To investigate the diagnosis and treatment of synchronous multiple primary lung cancer(sMPLC).Methods Twenty-nine patients with sMPLC who underwent surgical resection in Jiangnan University Hospital from January 2012 to December 2015 were randomly selected,including 17 males and 12 females.The number of cancer lesions was 2 in 23 cases,>2 in 6 cases;the tumor was located in the same side in 15 cases,and bilateral in 14 cases,and the corresponding surgical treatment were given,and the survival time and survival rate were counted.Results Twenty-nine patients underwent successful thoracoscopic surgery.Among them,15 patients underwent standard lobectomy and sublobectomy,and 14 patients underwent subtotal lobectomy.The average survival time was 33 months and the 3-year overall survival rate was 58.6%.The prognosis of patients with bilateral primary lung cancer were slightly worse than that of unilateral.Conclusions Clinicians should pay more attention to sMPLC.Early diagnosis and active treatment with operation can achieve longer survival time.