小儿平喘方联合西药治疗小儿支气管哮喘急性发作期临床研究

Clinical Study on Xiao’er Pingchuan Prescription Combined with Western Medicine for Acute Attack of Bronchial Asthma in Children

目的:观察小儿平喘方雾化吸入联合硫酸沙丁胺醇气雾剂治疗支气管哮喘急性发作期的效果。方法:将96例风寒束肺证患儿采用随机数字表法分为观察组和对照组各48例,2组均予硫酸沙丁胺醇气雾剂治疗,进行雾化吸入护理措施指导,观察组加用小儿平喘方雾化吸入,疗程均为7 d。2组均于7 d疗程结束后4周进行儿童哮喘控制测试(C-ACT),每天记录3次最大呼气峰流量(PEF)情况,统计PEF波动情况;治疗前后评定哮喘急性发作时病情严重程度评分。比较2组的临床疗效和护理满意度。结果:治疗后,观察组的疾病疗效与哮喘控制情况均优于对照组(P<0.05)。2组PEF昼夜波动率均小于治疗前(P<0.01),病情严重程度评分较治疗前下降(P<0.01)。观察组PEF昼夜波动率小于对照组(P<0.01),病情严重程度评分低于对照组(P<0.01)。观察组护理满意度高于对照组(P<0.05)。结论:在使用硫酸沙丁胺醇气雾剂的同时加用小儿平喘方雾化吸入可有效减轻病情程度,控制哮喘发作,改善肺功能。

Objective: To observe the effect of the therapy of aerosol inhalation of Xiao’er Pingchuan prescription combined with salbutamol sulphate aerosol on acute attack of bronchial asthma. Methods: A total of 96 children with syndrome of wind-cold fettering the lung were randomly divided into the observation group and the control group,48 cases in each group. Both groups were treated with salbutamol sulphate aerosol and given guidance on the nursing measures of aerosol inhalation. The observation group was additionally treated with aerosol inhalation of Xiao’er Pingchuan prescription.Both groups were treated for seven days. Four weeks after the treatment course,Children’s Asthma Control test(C-ACT)was performed in both groups;the Peak Expiratory Flow(PEF) was recorded three times a day,and the PEF fluctuation was counted;the severity score of acute asthma was assessed before and after treatment. The clinical effect and nursing satisfaction were compared between the two groups. Results:After treatment,the curative effect and asthma control in the observation group were better than those in the control group(P<0.05). The day-night volatility of PEF in both groups was lower than that before treatment respectively(P<0.01), and the severity score of acute asthma attack in both groups was decreased when compared with that before treatment respectively(P<0.01). The day-night volatility of PEF in the observation group was lower than that in the control group(P<0.01),and the severity score of acute asthma attack was lower than that in the control group as well(P<0.01). The nursing satisfaction in the observation group was higher than that in the control group(P<0.05). Conclusion:The additional application of aerosol inhalation of Xiao’er Pingchuan prescription based on salbutamol sulphate aerosol,can reduce the severity of asthma,control its attack and improve lung function.