摘要
A nickel-catalyzed reductive coupling of aldehydes with aikynes using 1-phenylethanol as reducing agent has been developed.The key achievement of this work is that we demonstrate environmentally benign 1-phenylethanol can serve as a viable alternative reducing agent to Et3B,ZnEt2 and R3SiH for the nickel-catalyzed reductive coupling reaction of aldehyde and alkynes.
基金
We thank the National Natural Science Foundation of China(Nos.21672107,91856104 and 21871145)
"the Fundamental Research Funds for the Central Universities",Nankai University(No.63191601)for financial support.
