四川地区藏族和汉族人群寄生虫感染诊断中的血细胞特征分析

Analysis of hemolytic characteristics in diagnosis of parasitic infection in Tibetan and Han populations in Sichuan area

目的分析四川地区藏族和汉族的寄生虫患者血细胞特征分布差异,及其与本族正常指标的差异。方法分析四川地区寄生虫患者125例(试验组,其中汉族82例,藏族43例)和同期未发现寄生虫感染的健康志愿者486例(对照组,其中汉族427例,藏族59例)的白细胞计数(WBC)、嗜酸性粒细胞百分率(E%)、血红蛋白含量(HGB)和血小板计数(PLT)均值差异。结果试验组中藏族人群和汉族人群的PLT分别为(270.09±133.84)×10^9和(198.90±78.10)×10^9·L^-1,E%分别为(2.43±1.54)%和(12.62±4.96)%,对照组中藏族人群和汉族人群的PLT分别为(237.88±91.03)×10^9和(178.26±59.68)×10^9·L^-1,差异均有统计学意义(均P<0.01)。试验组和对照组中汉族人群的WBC分别为(8.44±7.25)×10^9和(6.39±1.94)×10^9·L^-1,E%分别为(12.62±4.96)%和(2.66±1.85)%,HGB分别为(141.17±21.00)和(150.28±14.16)g·L^-1,差异均有统计学意义(均P<0.01)。结论藏族人群和汉族人群的血细胞计数均值和异常率均存在一定差异;汉族人群的差异明显,有利于寄生虫病诊断;而藏族人群的差异并不显著,在寄生虫病诊断中要加以判断。

Objective To analyze the difference of blood cell characteristics between Tibetan and Han parasite patients in Sichuan area and the difference between them and their normal indexes.Methods The differences of white blood cell(WBC),eosinophil percentage(E%),hemoglobin(HGB)and platelet(PLT)were analyzed in 125 patients with parasites in Sichuan(treatment group,including 82 Han nationality and 43 Tibetan)and 486 healthy volunteers without parasite infection in the same period(control group,including 427 Han nationality and 59 Tibetan).Results The PLT of Tibetan and Han nationality in treatment group were(270.09±133.84)×10^9 and(198.90±78.10)×10^9·L^-1,E%were(2.43±1.54)%and(12.62±4.96)%,the PLT of Tibetan and Han in control group were(237.88±91.03)×10^9 and(178.26±59.68)×10^9·L^-1,the differences of treatment and control groups were statistically significant(all P<0.01).The WBC of Han nationality in treatment and control groups were(8.44±7.25)×10^9 and(6.39±1.94)×10^9·L^-1,E%were(12.62±4.96)%and(2.66±1.85)%,HGB were(141.17±21.00)and(150.28±14.16)g·L^-1,the differences were statistically significant(all P<0.01).Conclusion There are statistic differences in the value and abnormal rate of blood cell count between Tibetan and Han population.The difference of Han population is obvious,which is beneficial to the diagnosis of parasitic diseases,while the difference of Tibetan population is not significant,which should be judged in the diagnosis of parasitic diseases.