慢性肾脏病患者高磷血症治疗进展

Progress in the treatment of hyperphosphatemia in patients with chronic kidney disease

慢性肾脏病(CKD)自被发现以来,其发病率一直高居不下,高磷血症作为其最常见的并发症之一,也是一直困扰临床的一大难题。血磷水平能否得到有效控制与CKD患者的预后和生存时间密切相关,因此对CKD高磷血症的综合治疗对CKD患者来说至关重要,本文将从饮食的控制、含磷药物的替换、磷结合剂的选择、透析的个体化和强化等方面简要综述高磷血症的治疗进展。

Chronic kidney disease(CKD)is one of the most urgent problems in global health since its discovery,which is characterized by high prevalence rate,multiple complications and poor long-term prognosis.And hyperphosphatemia,which has not been overcome clinically,is the most common complications of CKD.Keeping blood phosphorus concentrations within a normal range is extremely important for CKD patients,which not only effectively improves their prognosis,but also extends their lifespan.This article will briefly review the progress in the treatment of hyperphosphatemia from the aspects of dietary control,replacement of phosphorus-containing drugs,comparison of phosphorus binders,excretion of urinary phosphorus,and intensification of dialysis and traditional Chinese medicine.