纤维蛋白(原)降解产物水平在孕晚期及产褥早期妇女中的变化

目的探讨血浆纤维蛋白(原)降解产物(FDP)水平在正常妊娠妇女的孕晚期及产褥早期中的价值。方法选取2017年6月至2018年9月间无妊娠并发症的正常妊娠妇女769例,分为阴道分娩组(408例)和剖宫产分娩组(361例)。剖宫产分娩组分为2个亚组,瘢痕子宫组176例,无瘢痕子宫组185例。应用免疫比浊法检测FDP水平并对结果进行分析。结果阴道分娩组:FDP水平在产褥早期则显著低于孕晚期(P<0.001)。产褥早期:剖宫产分娩组与阴道分娩组比较,FDP水平显著升高(P<0.001)。剖宫产分娩亚组分析:无瘢痕子宫组与瘢痕子宫组比较,产褥早期的FDP水平显著升高(P<0.05)。结论妊娠妇女FDP水平在孕晚期与瘢痕子宫无关。在产褥早期的变化趋势与分娩方式相关,剖宫产分娩方式FDP水平显著升高。

Objective Discussed the value of plasma fibrinogen degradation products(FDP)in healthy pregnant women with the third trimester and early puerperium.Methods The healthy pregnant women(769 subjects)excluding pregnancy complications were enrolled from June 2017 to September 2018,including vaginal delivery group(408 subjects),cesarean section delivery group(361 subjects).The cesarean section delivery group was scar group(176 subjects)and no scar group(185 subjects).FDP was detected by immunoturbidimetry and the results were analyzed.Results Vaginal delivery group:FDP was significant lower in the early puerperium compared with the third trimester(P<0.001).The early puerperium:FDP was significant higher in the cesarean section delivery group compared with vaginal delivery group(P<0.001).Compared with scar group,FDP was significant higher in early puerperium with no scar group(P<0.05).Conclusion FDP was unrelated to the scar in the third trimester.The FDP level of cesarean section further increased in the early puerperium which was related to the delivery mode.