临床药师干预对肾内风湿免疫科抗菌药物使用强度的成效分析

Effect analysis of clinical pharmacist intervention on antimic use density in department of intrarenal rheumatology and immunology

目的 探讨临床药师干预前后肾内风湿免疫科住院患者抗菌药物使用强度的变化,提高肾内风湿免疫科抗菌药物的合理使用.方法 回顾性调查干预前(2018年6~12月)我院肾内风湿免疫科所有抗菌药物数据,通过点评该科抗菌药物病历,找出原因、确定目标,制定对策并实施干预,临床药师积极参与抗菌药物管理的全过程,比较干预前与干预后(2019年1~7月)住院患者抗菌药物使用强度及抗菌药物不合理用药情况.结果 干预后,肾内风湿免疫科抗菌药物使用强度、抗菌药物费用、抗菌药物不合理用药均低于干预前,差异有统计学意义(P<0.01).结论 临床药师的积极参与可有效降低抗菌药物使用强度及费用,提高了抗菌药物在肾内风湿免疫科的合理应用.

Objective To explore the changes of antibiotic use intensity of hospitalized patients in department of intrarenal rheumatology and immunology before and after intervention by clinical pharmacists,so as to improve the rational use of antibiotic in department of intrarenal rheumatology and immunology.Methods The data of all antibacterial drugs in the department of intrarenal rheumatology and immunology in our hospital before the intervention(June to December 2018)were retrospectively investigated.Through reviewing the medical records and prescriptions of antibacterial drugs in this department,the reasons were found out,the objectives were determined,the countermeasures were formulated and the intervention was implemented.Clinical pharmacists actively participated in the whole process of antibacterial drug management.The antibacterial drug use intensity and irrational use of antibacterial drugs of hospitalized patients before and after the intervention(January to July 2019)were compared.Results After the intervention,the use intensity,cost and irrational use of antibacterial drugs in department of intrarenal rheumatology and immunology were all lower than those before the intervention,and the differences were statistically significant(P<0.01).Conclusion The active participation of clinical pharmacists can effectively reduce the use intensity and cost of antibacterial drugs and improve the rational application of antibacterial drugs in department of intrarenal rheumatology and immunology.