清肺排毒汤致新型冠状病毒肺炎患者高钾血症

Hyperkalemia caused by Qingfei Paidu decoction(清肺排毒汤)in a patient with novel coronavirus pneumonia

1例23岁男性患者因新型冠状病毒肺炎给予莫西沙星、注射用重组人干扰素α-2b和洛匹那韦/利托那韦治疗7 d,血钾未见异常。停用莫西沙星,给予清肺排毒汤,患者血钾开始升高。服用清肺排毒汤第10天,患者血钾5.7 mmol/L,诊断为高钾血症。给予胰岛素注射液4 U入5%葡萄糖注射液250 ml静脉滴注1次,6 h后,患者血钾降至5.0 mmol/L,2 d后降至4.6 mmol/L。之后,患者血钾复升,并于服用汤药第17天升至5.4 mmol/L。当天及2 d后每天给予1次胰岛素治疗(用法用量同前),血钾未再升高。住院28 d,患者新型冠状病毒肺炎痊愈,停药出院。

A 23-year-old male patient received moxifloxacin,recombinant human interferonα-2b for injection,and lopinavir and ritonavir for 7 days for novel coronavirus pneumonia.There was no abnor-malityof serum potassium.Moxifloxacin was stopped,Qingfei Paidu decoction(清肺排毒汤)was given,and then the patient′s serum potassium began to rise.On day 10 after taking the decoction,laboratory tests showed serum potassium 5.7 mmol/L and the patient was diagnosed with hyperkalemia.Insulin injection 4 U diluted to 5%glucose injection 250 ml was given once by IV infusion,and then the serum potassium decreased to 5.0 mmol/L 6 hours later and 4.6 mmol/L 2 days later.After 5 days,the serum potassium rose again and finally to 5.4 mmol/L on day 17 after taking the decoction.Insulin was given once that day and 2 days later once daily according to the previous method.Then the serum potassium decreased and did not rise again.The patient recovered from novel coronavirus pneumonia and was discharged on day 28 after hospitalization.