胆囊癌的诊治进展

Diagnosis and treatment of gallbladder cancer

胆囊癌是胆道系统最常见的恶性肿瘤,具有早期临床表现不典型、进展快、预后差的特点。胆囊癌无特定的标志物,其术前诊断主要依靠影像学检查,而PET-CT在局部晚期胆囊癌的转移灶检出中更有优势。外科手术治疗仍是主要治疗手段,但多数患者就诊时已失去手术切除的机会。近年来,国内外就胆囊癌的诊断和治疗进行了大量研究,靶向治疗和免疫治疗为胆囊癌提供了新的治疗手段。本文就胆囊癌的诊断和治疗作一综述。

Gallbladder carcinoma is the most common malignant tumor of the biliary tract system.It is characterized by atypical early clinical manifestations,rapid progress and poor prognosis.There is no specific marker for gallbladder cancer,and its preoperative diagnosis mainly relies on imaging examination,while pet-ct is more advantageous in detecting the metastasis of locally advanced gallbladder cancer.Surgical treatment is still the main treatment,but most patients have lost the opportunity of surgical resection by the time of treatment.In recent years,there have been a lot of researches on the diagnosis and treatment of gallbladder cancer at home and abroad.This paper reviews the diagnosis and treatment of gallbladder carcinoma.