基于“补五脏之阴”刍议覆盆子在妇科杂病中的应用

On the Application of Fupenzi(Raspberry)in Gynecology Miscellaneous Diseases

通过研究覆盆子的源流证治及历代医家的述评与临床证治,结合覆盆子在妇科杂病中的临床应用及其在女性生殖系统的作用,从朱丹溪"阳常有余,阴常不足"、覆盆子滋阴补肾等角度阐释覆盆子补五脏之阴的作用,发挥覆盆子补益肾阴、填精补髓、固摄肾气、养血调经、调理冲任之效,以期从"补五脏之阴"角度为妇科杂病、女性生殖系统疾病在妇人月经不调、经闭、崩漏、不孕、滑胎、绝经前后诸症、带下病及妇人产后小便不禁等疾病提供新的思路和方法。现代研究从覆盆子中分离出萜类、黄酮、生物碱、香豆素类等成分,进行药效学筛选和相关研究,在抗肿瘤、抗衰老、清除自由基等方面有明确的活性,其寡糖、多糖、核苷类成分有其补肾滋阴的物质基础,其诸多功效也被现代药理研究所证实。覆盆子在妇科生殖系统的调节、生殖激素合成的促进、妇科肿瘤的防治、抗氧化、延缓衰老、促进代谢等方面治疗有重要的药用价值,在女性生殖系统方面亦有者广泛的临床应用,需要不断深入的研究和开发利用。

Through the study of origin for Fupenzi(raspberry)and subject review of past dynasties and clinical practice,combined with Fupenzi(raspberry)clinical application in gynecologic diseases and its role in the female reproductive system,it explained the effect on tonifying five Zang-organs of Fupenzi(raspberry)including tonifying kideny and Yin,supplementing essence and marrow,consolidating kidney Qi,nourishing blood and regulating menstruation and regulating Chong and Ren meridians from ZHU Danxi’s theory that Yang often being excess while Yin often deficiency as well as the theory that Fupenzi(raspberry)can nourish Yin and tonify kidney.It is expected to provide new ideas and methods for gynecological miscellaneous diseases or female reproductive system diseases in women,such as irregular menstruation,menorrhagia,leakage,infertility,slipping fetus,postmenopausal diseases,and postpartum urination.Modern research isolated terpenoids,flavonoids,alkaloids and coumarin from Fupenzi(raspberry).These components were proved the activity of scavenging free radicals,the anti-tumor and anti-aging by the pharmacodynamics researches.Its ingredients like oligosaccharides,polysaccharides and nucleosides have its kidney-nourishing material base and its benefits also have been confirmed by the modern pharmacological research.Fupenzi(raspberry)has important medicinal value in the gynecological reproductive system regulation,the promotion of reproductive hormone synthesis,the prevention and treatment of gynecological tumors,anti-oxidation,anti-aging,promoting metabolism and other aspects.In the female reproductive system,it also has a wide range of clinical applications and needs to continue in-depth research and development and utilization.