大同市2011-2018年预防梅毒母婴传播信息工作分析

Information assessment of preventing syphilis maternal-neonatal transmission from 2011 to 2018 in Datong

目的通过分析大同市预防梅毒母婴传播工作信息,以及孕产妇人群中梅毒的流行现状,有针对性地对梅毒感染孕产妇给予苄星青霉素规范治疗,为阻断梅毒母婴传播提供依据。方法收集整理2011-2018年大同市预防梅毒母婴传播信息工作资料,分成2011-2013年和2014-2018年2个阶段,对梅毒感染孕产妇所生的婴幼儿给予苄星青霉素(青霉素皮试阳性者,可选用红霉素)进行预防性治疗并定期随访,对结局进行分析。结果孕期梅毒检测率逐年上升,孕早期梅毒检测率仍然很低,检出梅毒感染孕产妇294例,双胎4例。梅毒感染孕产妇所生的婴儿280例,死胎14例,死产4例,7天内死亡9例,随访中死亡2例,诊断先天梅毒儿4例。结论预防梅毒母婴传播,迫切需要加大健康教育宣传力度,提高孕早期知晓率、咨询率和检测率。在孕早期进行梅毒血清学检测,发现感染即采取有效措施规范治疗,可最大程度地减少梅毒母婴传播的发生,对预防不良妊娠结局有重要意义。

Objective To analyze the work information for preventing syphilis maternal-neonatal transmission in Datong,as well as the popularity of syphilis among the pregnant women,provide benzathine penicillin to those pregnant women that had been infected syphilis as a standard treatment,provide evidence for blocking maternal-neonatal transmission of syphilis.Methods Data on the prevention of mother-to-child transmission of syphilis in Datong from 2011 to 2018 were collected and sorted out,and 2011-2013 and 2014-2018 were divided into 2 stage respectively to analyze preventive treatment and regular follow-up for infants born to pregnant women with syphilis infection were given benzathine penicillin(erythromycin can be selected for penicillin skin test positive).Results The detection rate of syphilis in pregnancy increased year by year,and the detection rate of syphilis in early pregnancy was still very low.The research showed that there were 294 pregnant women had been detected syphilis infection and 4 of them were twins.Among 280 children born to pregnant women with syphilis infection,14 were stillborn,4 were stillborn,9 died within 7 days and 2 died during follow-up.Four cases of congenital syphilis were diagnosed.Conclusion To prevent mother-to-child transmission of syphilis,there is an urgent need to increase health education and publicity efforts,improve the early pregnancy awareness rate,consultation rate and detection rate.Serological examination of syphilis in the early pregnancy,the discovery of infection that take effective measures to standardize treatment can minimize the occurrence of transmission of syphilis from mother to child,prevent adverse pregnancy outcome has important significance.