腰硬联合麻醉对老年膝骨性关节炎患者术后认知功能的影响

Impact of Combined Spinal-Epidural Anesthesia on Postoperative Cognitive Function of Elderly Patients with Knee Osteoarthritis

目的探讨腰硬联合麻醉对老年膝骨性关节炎患者术后认知功能的影响。方法选取2017年6月至2019年6月期间在我院接受手术治疗的120例老年膝骨性关节炎患者作为研究对象,随机分为两组各60例。对照组实施全身麻醉,观察组实施腰硬联合麻醉。比较两组术前、术后24 h、术后48 h的认知功能,比较两组的深静脉血栓发生率。结果术前,两组的MMSE评分比较,差异无统计学意义(P>0.05);术后24 h、 48 h,两组的MMSE评分均有所降低,但观察组的MMSE评分均显著高于对照组(P <0.05)。观察组的深静脉血栓发生率为6.67%,显著低于对照组的20.00%(P <0.05)。结论腰硬联合麻醉用于老年膝骨性关节炎患者中,对患者的术后认知功能影响较小,可减少深静脉血栓的发生。

Objective To explore the impact of combined spinal-epidural anesthesia on postoperative cognitive function of elderly patients with knee osteoarthritis.Methods 120 cases of elderly patients with knee osteoarthritis who received surgical treatment in our hospital from June 2017 to June 2019 were selected as research objects and randomly divided into two groups,with 60 cases in each group.The control group was given general anesthesia,and the observation group was given combined spinal-epidural anesthesia.The cognitive function of the two groups was compared before surgery,24 h after surgery and 48 h after surgery,and the incidence of deep vein thrombosis was compared between the two groups.Results No significant difference was found between the two groups in MMSE score before surgery(P>0.05);24 h and 48 h after surgery,MMSE scores of both groups reduced,but MMSE scores of the observation group were significantly higher than those of the control group(P<0.05).The incidence of deep vein thrombosis in the observation group was 6.67%,significantly lower than 20.00%in the control group(P<0.05).Conclusions Combined spinal-epidural anesthesia applied in elderly patients with knee osteoarthritis has little impact on patients'postoperative cognitive function,and can reduce the incidence of deep vein thrombosis.