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加巴喷丁联合硫酸吗啡缓释片治疗癌性神经病理性疼痛的临床研究 被引量:1

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摘要 目的分析加巴喷丁联合硫酸吗啡缓释片治疗癌性神经病理性疼痛的临床效果。方法收集2018年3月至2020年3月该院癌性神经病理性疼痛患者64例,分成观察组和对照组,每组32例。对照组采用硫酸吗啡缓释片单纯治疗,观察组采用加巴喷丁联合硫酸吗啡缓释片治疗,对比两组患者的治疗效果、不良反应发生率、治疗前后睡眠质量以及治疗前后疼痛程度。结果观察组的治疗效果为93.75%,高于对照组的71.88%(P<0.05)。观察组的恶心、呕吐、便秘等不良反应发生率为9.38%,低于对照组的31.25%(P<0.05)。治疗前、治疗后24 h、治疗后48 h、治疗后7 d、治疗后15 d,观察组的疼痛程度、睡眠质量评分均要低于对照组(P<0.05)。结论癌性神经病理性疼痛通过加巴喷丁联合硫酸吗啡缓释片的临床效果显著,能够有效缓解患者的疼痛程度。
作者 李忠铭
出处 《重庆医学》 CAS 2020年第S01期289-290,共2页 Chongqing medicine
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