地佐辛静脉自控镇痛对剖宫产产妇术后疼痛程度及血清泌乳素浓度的影响

Effect of patient-controlled intravenous analgesia with dizosin on pain degree and serum prolactin concentration after cesarean section

目的 探讨地佐辛静脉自控镇痛对剖宫产产妇术后疼痛程度及血清泌乳素浓度(PRL)的影响.方法 选取2016年3月至2018年3月在本院行剖宫产术产妇106例,按照随机数字表法分成对照组和观察组,各53例.对照组给予常规静脉自控镇痛,观察组接受地佐辛静脉自控镇痛,比较两组疼痛程度、血清泌乳素(PRL)和不良反应.结果 术后24 h、48 h观察组视觉模拟评分法(VAS)低于对照组,血清泌乳素(PRL)水平高于对照组,差异具有统计学意义(P<0.05);观察组不良反应总发生率为5.66%(3/53),低于对照组的18.87%(10/53),差异具有统计学意义(P<0.05).结论 地佐辛静脉自控镇痛可有效缓解行剖宫产术后产妇的疼痛程度,提高血清泌乳素浓度,降低不良反应发生率,利于产妇产后恢复.

Objective To investigate the effect of patient-controlled intravenous analgesia with dizocine on pain degree and serum prolactin concentration(PRL)after cesarean section.Methods 106 parturients who underwent caesarean section in our hospital from March 2016 to March 2018 were selected and divided into control group and observation group according to random number table method,there were 53 cases in each groups.The control group was given the commonly used self-controlled analgesia,while the observation group received the intravenous self-controlled analgesia of dizosin.The pain degree,serum prolactin(PRL)and adverse reactions were compared between the two groups.Results The visual analogue score(VAS)of the observation group was lower than that of the control group at 24 h and 48 h after operation,and the level of serum prolactin(PRL)was higher than that of the control group(P<0.05).The total incidence of adverse reactions in the observation group was 5.66%(3/53)lower than that in the control group 18.87%(10/53),and the difference was statistically significant(P<0.05).Conclusion Patient-controlled intravenous analgesia with dizosin can effectively relieve the pain of parturients after cesarean section,increase the serum prolactin concentration,reduce the incidence of adverse reactions,and facilitate the recovery of parturients.