荆花胃康胶丸联合四联疗法治疗幽门螺旋杆菌阳性消化性溃疡

Jinghua Weikang Pill Combined with Quadruple Therapy in the Treatment of Helicobacter pylori-positive Peptic Ulcer

目的探究荆花胃康胶丸联合四联疗法治疗幽门螺旋杆菌阳性消化性溃疡的治疗效果。方法将2016年6月—2018年5月治疗的幽门螺旋杆菌阳性消化性溃疡患者76例随机分为观察组和对照组。对照组使用常规的四联疗法;观察组采取与对照组相同的四联疗法情况下外加荆花胃康胶丸辅助治疗。在停药4周以后,检测2组患者的幽门杆菌的根除率。结果观察组总有效率为92.1%,而对照组的总有效率为76.3%。并且观察组的幽门螺旋杆菌转阴率(86.8%)也远高于对照组的转阴率(68.4%)。2组对比差异有统计学意义(P<0.05)。结论荆花胃康胶丸与四联疗法的共同使用对幽门螺旋杆菌阳性消化性溃疡的治疗更加安全、彻底,值得在临床上广泛推广。

Objective To explore the effect of Jinghua Weikang pill combined with quadruple therapy for Helicobacter pylori-positive peptic ulcer.Methods A total of 76 patients with Helicobacter pylori positive peptic ulcer treated from June 2016 to May 2018 were randomly divided into observation group and control group.The control group received conventional quadruple therapy.The observation group was treated with the same quadruple therapy as the control group,supplemented with Jinghua Weikang pill.After four weeks the withdrawal,the detection of Helicobacter pylori eradication rate of the two groups of patients was carried out.Results The total effective rate was 92.1%in the observation group and 76.3%in the control group.The negative conversion rate of H.pylori in the observation group(86.8%)was also much higher than that in the control group(68.4%).The difference between the two groups was statistically significant(P<0.05).Conclusion The common use of Jinghua Weikang pill and quadruple therapy is more safe and thorough in the treatment of helicobacter pylori positive peptic ulcer,which is worthy of extensive promotion in clinical practice.